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Showing posts from May 31, 2023

Principles of Centrifugation

  CENTRIFUGATION Centrifugation is a separation process which uses the action of centrifugal force (a force which acts on a body moving in a circular path and is directed towards the centre around which the body is moving) to promote accelerated settling of particles in a solid-liquid mixture. Centrifugation is the process where a mixture is separated through spinning. During Centrifugation, the solid particles were separated from the liquid particles. In 1864, Antonin Prandl invented the first dairy centrifuge in order to separate cream from milk. In 1879, Gustaf de Laval demonstrated the first continuous centrifugal separator, making its commercial application feasible. CENTRIFUGE The Centrifugation process was carried out in conical tubes (centrifuge tubes) with the help of an instrument named “Centrifuge”. The centrifuge separates the particles from a solution according to their size, shape, density, viscosity of the medium and rotor speed. A centrifuge is used to separate the pa